Purple Heart was originally named Setcreasea pallida by Joseph Nelson Rose in 1911. Rose is best known for his collaboration with Nathaniel Lord Britton, the first director of the New York Botanical Garden. Britton and Rose named numerous cacti species. Rose became the first full-time botanist for the Smithsonian Institution in 1894. He was replaced as the Assistant Curator of the National Herbarium after one year. In 1899, Rose wrote a book, Notes on Useful Plants of Mexico.
D.R. Hunt of the Royal Botanic Garden, Kew reclassified Purple Heart placing it in the genus, Tradescantia, in 1975.